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07-17-2014, 02:42 AM
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NeoTillichian Hierophant & Partisan Hack
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Join Date: Dec 2005
Location: Iowa
Gender: Male
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Re: Drive by science
Biological Pacemaker
Quote:
By injecting a gene into a pig’s heart, scientists have created a “biological pacemaker” that can regulate heartbeats, an achievement that eventually may lead to an alternative to electronic pacemakers in some people.
The technique may also prove to be a promising example of gene therapy, which so far has shown glimmers of success in just a few other conditions.
Researchers at the Cedars-Sinai Heart Institute in Los Angeles reported Wednesday that they had injected a gene into a tiny section of pigs’ hearts and were able to temporarily reprogram ordinary heart cells into rhythm-generating cells. Human trials of the technique are at least three years away, and if successful, the approach would be, at least at first, limited to a small subset of pacemaker users.
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(More information at the link)
This is pretty cool, if they can make it work long term.
__________________
Old Pain In The Ass says: I am on a mission from God to comfort the afflicted and afflict the comfortable; to bring faith to the doubtful and doubt to the faithful.
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07-17-2014, 05:34 AM
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I'm Deplorable.
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Re: Drive by science
Quote:
Originally Posted by Angakuk
Biological Pacemaker
Quote:
By injecting a gene into a pig’s heart, scientists have created a “biological pacemaker” that can regulate heartbeats, an achievement that eventually may lead to an alternative to electronic pacemakers in some people.
The technique may also prove to be a promising example of gene therapy, which so far has shown glimmers of success in just a few other conditions.
Researchers at the Cedars-Sinai Heart Institute in Los Angeles reported Wednesday that they had injected a gene into a tiny section of pigs’ hearts and were able to temporarily reprogram ordinary heart cells into rhythm-generating cells. Human trials of the technique are at least three years away, and if successful, the approach would be, at least at first, limited to a small subset of pacemaker users.
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(More information at the link)
This is pretty cool, if they can make it work long term.
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Long term would be good, but to do that they would need to change the basic genetic structure of the tissue. The article sounds like a temporary patch, not a permanent fix.
Pacing is only part of the problem in some cases. Sometimes when fibrillation occurs, pacing will not bring the heart out of it, and the defibrillator must shock the heart to stop it so it will start up again with a normal heart beat. I've been through both and I really don't want to experience either again. I suppose that pacing is good for the less severe cases, but I don't think it would be enough for me.
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The highest form of ignorance is when you reject something you don’t know anything about. Wayne Dyer
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07-21-2014, 07:37 AM
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A Very Gentle Bort
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Join Date: Jan 2005
Location: Bortlandia
Gender: Male
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Re: Drive by science
__________________
\V/_ I COVLD TEACh YOV BVT I MVST LEVY A FEE
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07-22-2014, 02:33 AM
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simple country microbiologist hyperchicken
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Join Date: Sep 2004
Location: georgia
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Re: Drive by science
Quote:
Originally Posted by Angakuk
Biological Pacemaker
Quote:
By injecting a gene into a pig’s heart, scientists have created a “biological pacemaker” that can regulate heartbeats, an achievement that eventually may lead to an alternative to electronic pacemakers in some people.
The technique may also prove to be a promising example of gene therapy, which so far has shown glimmers of success in just a few other conditions.
Researchers at the Cedars-Sinai Heart Institute in Los Angeles reported Wednesday that they had injected a gene into a tiny section of pigs’ hearts and were able to temporarily reprogram ordinary heart cells into rhythm-generating cells. Human trials of the technique are at least three years away, and if successful, the approach would be, at least at first, limited to a small subset of pacemaker users.
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(More information at the link)
This is pretty cool, if they can make it work long term.
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I would rate it highly unlikely as working long term. I can not be sure because the technical details are lacking in the article but it seems they are injecting dna into the heart that is then transcribed and translated into a protein. Cells don't like floating DNA, it gets degraded. There are ways to slow this but I am surprised that it lasts as long as it does.
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09-04-2014, 11:11 AM
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forever in search of dill pickle doritos
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Re: Drive by science
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09-22-2014, 05:21 PM
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Now in six dimensions!
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Join Date: Jan 2005
Location: The Cotswolds
Gender: Male
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Re: Drive by science
Quote:
Originally Posted by Dragar
Quote:
Originally Posted by lpetrich
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And it looks like it was fuss over nothing (or more probably, over galaxy dust). Read the paper here.
"...and its spectral index is found to be consistent with that of the CMB, disfavoring dust at 1.7 σ..."
So yeah, 1.7 sigma is not exactly solid. Good blog coverage here.
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And finally, it looks like the latest Planck results have pretty much quashed any claims of gravitational wave detection.
Bet the media are silent on this...
(Oh, there's a BBC article hiding.)
__________________
The miracle of the appropriateness of the language of mathematics for the formulation of the laws of physics is a wonderful gift which we neither understand nor deserve. -Eugene Wigner
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09-22-2014, 08:32 PM
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Solipsist
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Join Date: Jul 2004
Location: Kolmannessa kerroksessa
Gender: Male
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Re: Drive by science
Quote:
Originally Posted by Dragar
Bet the media are silent on this...
(Oh, there's a BBC article hiding.)
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Major news outlet fails to support poster's presumption of lack of reporting of negative results in science
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10-04-2014, 08:19 PM
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I said it, so I feel it, dick
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Join Date: Jul 2004
Location: Here
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Re: Drive by science
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10-04-2014, 08:23 PM
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California Sober
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Join Date: Jul 2004
Location: Silicon Valley
Gender: Bender
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Re: Drive by science
Wow, that's just mind-blowing. What a time to be alive!
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12-18-2014, 05:57 AM
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I said it, so I feel it, dick
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Join Date: Jul 2004
Location: Here
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Re: Drive by science
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12-20-2014, 01:11 PM
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Solipsist
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Join Date: Jul 2004
Location: Kolmannessa kerroksessa
Gender: Male
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Re: Drive by science
NASA Just Emailed A Wrench To The International Space Station | IFLScience
Awesome.
Of course, there'll still be naysayers who'll insist the future hasn't really arrived until we can email flying cars to each other.
Before that, we'll have this:
Instead of going to the toolbox / garage for a particular tool, I'll just print another one where I am. Like WhatsApping my daughter instead of calling up the stairs.
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12-21-2014, 02:13 PM
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puzzler
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Join Date: Aug 2004
Location: UK
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Re: Drive by science
Saw an article about this on the BBC website, although they have their figures wrong.
It was the shortest day (longest night) of the year in the northern hemisphere (winter solstice) yesterday, but mornings will continue to get darker and later until early January; why?
It's because of the earth's elliptical orbit - we're closer to the sun in winter than summer and the earth is moving around its orbit faster.
The earth always takes about 23 hours 56 minutes and 4.1 seconds to spin once (relative to the stars) and the extra 4 minutes that make up a day are due to the earth having to turn a little bit extra to present the same face back to the sun, having moved around its orbit. Because the earth's speed varies over a year, a solar day is not always the same length. December 22nd is about fifty one seconds longer than September 16th. The cumulative effect leads to clocks being up to sixteen minutes out, compared to a sundial.
And that explains the darker mornings after the solstice - although December 21st was the shortest day, and the sun will start to rise sooner each day after that, at the moment all our clocks are running about half a minute fast per day, compared to real solar time as measured by a sundial, and that discrepancy is big enough to override the lengthening days for another ten days or so.
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Last edited by ceptimus; 12-21-2014 at 02:48 PM.
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Thanks, from:
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beyelzu (03-03-2015), Crumb (12-21-2014), Dragar (12-21-2014), Ensign Steve (01-01-2015), fragment (12-21-2014), Janet (12-22-2014), JoeP (12-21-2014), slimshady2357 (12-21-2014), Sock Puppet (12-29-2014), SR71 (12-30-2014), The Lone Ranger (01-06-2015)
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12-21-2014, 06:01 PM
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Adequately Crumbulent
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Join Date: Jan 2005
Location: Cascadia
Gender: Male
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Re: Drive by science
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12-23-2014, 07:15 AM
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Forum Killer
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Re: Drive by science
Quote:
Originally Posted by slimshady2357
New mushroom shaped creatures found off coast of Australia that defy classification!
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We need to get plankton portal's s oceanography rig out by the australian coast, stat. It can photograph large stretches of sea without net-trawling it and specializes in catching semitransparent things by shadowgraphy. If it's there, it could find them.
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12-29-2014, 04:47 PM
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Mr. Condescending Dick Nose
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Join Date: May 2007
Location: Augsburg
Gender: Male
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Re: Drive by science
A Jumbo Jet is in trouble. I'm hoping that someone who knows stuff can tell me what might the perceived advantage be, to crew, or passengers, or airline shareholders, of returning to the departure airport rather than performing the problematic landing at the destination airport. I can't see the weather at Gatwick being better than at Vegas.
Picture 12.png
__________________
... it's just an idea
Last edited by mickthinks; 12-29-2014 at 04:58 PM.
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12-29-2014, 05:04 PM
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A Very Gentle Bort
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Join Date: Jan 2005
Location: Bortlandia
Gender: Male
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Re: Drive by science
If I'm reading it right, in this specific case it seems like the landing gear was stuck somewhere between fully extended and fully retracted. That would definitely cause a problem with fuel efficiency and probably flight dynamics. It could possibly even cause more damage to the airframe.
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\V/_ I COVLD TEACh YOV BVT I MVST LEVY A FEE
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12-29-2014, 07:52 PM
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puzzler
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Join Date: Aug 2004
Location: UK
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Re: Drive by science
That. But even if the landing gear had stowed away properly (but they somehow knew that it wouldn't come down again right) then they would probably have preferred the plane to land at a home airport rather than a foreign one, so they could have their own engineers work on repairs in their own hanger/workshop.
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01-06-2015, 06:31 AM
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Adequately Crumbulent
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Join Date: Jan 2005
Location: Cascadia
Gender: Male
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Re: Drive by science
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01-06-2015, 07:24 AM
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A Very Gentle Bort
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Join Date: Jan 2005
Location: Bortlandia
Gender: Male
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Re: Drive by science
The program they used is phat.
__________________
\V/_ I COVLD TEACh YOV BVT I MVST LEVY A FEE
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01-06-2015, 08:48 PM
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Jin, Gi, Rei, Ko, Chi, Shin, Tei
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Re: Drive by science
Quote:
The image taken by the Hubble Space Telescope has an amazing 1.5 billion pixels that would require 600 HD television screens to display in full.
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And yet, the galaxy is so incomprehensibly huge that there are hundreds of stars per pixel. And Andromeda is only one of perhaps 100 billion galaxies in the observable Universe.
I love these sorts of things, because I think it's good for us to every now and again be reminded that the Universe is incomprehensibly vast.
__________________
“The greatest way to live with honor in this world is to be what we pretend to be.” -- Socrates
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01-06-2015, 09:09 PM
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I read some of your foolish scree, then just skimmed the rest.
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Join Date: Jan 2005
Location: Bay Area
Gender: Male
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Re: Drive by science
That's the insane thing. It would still be impressive if there were only 10 galaxies but there's actually 100x as many as there are pixels in that image.
One day I want to setup a mini planetarium with a decent projector and images like this and the Hubble deep field will be shown for a bunch of tripping people and I will get to hear the sound of their brains exploding.
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01-11-2015, 06:17 PM
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Now in six dimensions!
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Join Date: Jan 2005
Location: The Cotswolds
Gender: Male
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Re: Drive by science
Quote:
Originally Posted by BrotherMan
The program they used is phat.
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An oft used tool for extracting individual objects from a image containing multiple is called SExtractor.
__________________
The miracle of the appropriateness of the language of mathematics for the formulation of the laws of physics is a wonderful gift which we neither understand nor deserve. -Eugene Wigner
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01-11-2015, 10:40 PM
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Counter
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Join Date: Oct 2007
Location: Utrecht, the Netherlands
Gender: Male
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Re: Drive by science
Hey, I know the guy who wrote the manual to that! It's my old college roomie
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02-27-2015, 04:13 PM
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I said it, so I feel it, dick
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Join Date: Jul 2004
Location: Here
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Re: Drive by science
Ancient Britons imported wheat 8000 years ago, new archeological evidence suggests | Science Recorder
Quote:
“Amongst our Bouldnor Cliff samples we found ancient DNA evidence of wheat at the site, which was not seen in mainland Britain for another 2,000 years,” said Dr. Allaby in a report by Scientific American. “This is incredibly exciting because it means Bouldnor’s inhabitants were not as isolated as previously thought. In fact, they were in touch, one way or another, with more advanced Neolithic farming communities in southern Europe.”
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02-27-2015, 04:29 PM
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Solipsist
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Join Date: Jul 2004
Location: Kolmannessa kerroksessa
Gender: Male
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Re: Drive by science
Probably just southern Europeans popping over for summer holidays.
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